Hailing from Manchester, Sharma Angel-Walfall was inspired to write by her aunt, novelist Karline Smith. She studied writing, directing and acting at university, and took occasional on-screen roles in programmes such as Lol. In 2015, Angel-Walfall won the Channel 4 New Writing Award, and she was subsequently selected to be part of the ScreenSkills New Writers Programme. This led her to join a number of writers' rooms, and her first script credit came on a 2017 episode of Hollyoaks. Angel-Walfall went on to contribute to shows including Sparks and Dreamland, and she served as a script consultant on Wolfe. She collaborated with Doctor Who showrunner Russell T Davies on The Well, a 2025 adventure featuring Ncuti Gatwa as the Fifteenth Doctor.